About Tool

This tool helps identify which prediabetes cluster (or subtype) you belong to, based on your clinical and metabolic profile. This tool is grounded in findings from our published research. It follows a precision medicine approach to assess better the risk of progression to type 2 diabetes and related conditions, such as liver and kidney diseases.

Note: This tool is intended for scientific and educational purposes only. It does not provide a clinical diagnosis or medical advice.


Objective

The primary goal is to classify individuals with prediabetes into distinct subphenotypes to support early risk assessment and personalized intervention strategies.

Required Input Parameters

  • OGTT glucose values (fasting, 1-hour and 2-hour)
  • HbA1c
  • Triglycerides
  • HDL cholesterol
  • LDL cholesterol
  • Waist circumference
  • Age

Identified Prediabetes Clusters

  • Cluster 1 – Young Overweight: Younger individuals with mild metabolic disturbances.
  • Cluster 2 – Isolated IFG: Characterized by impaired fasting glucose with the lowest diabetes risk.
  • Cluster 3 – Age-Related: Predominantly older individuals with moderate risk factors.
  • Cluster 4 – High Glycemia: Highest glucose and lipid levels; highest risk of diabetes progression.
  • Cluster 5 – Obesity and Dyslipidemia: Marked by obesity and abnormal lipid profiles, with elevated risk.

Prediabetes Characteristics

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Note: This tool is subject of ongoing research. Do not draw any definitive conclusions from the results and discuss everything with your attending physician.